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New brain maps on EBRAINS show organizational principles of the prefrontal cortex

Probability maps and Maximum Probability Map in the DLPFC.

Newly published new brain maps identify five new areas within the dorsolateral prefrontal cortex (DLPFC), that plays a crucial role in executive functions, including working memory, decision-making, and attention. The new study introduces 3D maps of cytoarchitectonic regions, enhancing our understanding of the prefrontal cortex's complexity.

The study is an important step toward deciphering the structural-functional organization of the human prefrontal cortex. By analyzing series of histological sections and employing state-of-the-art statistical techniques, Bruno & Lothmann et al. identified and mapped five new areas within the DLPFC, and revealed their variations across brains. The three-dimensional maps will be part of the next release of the Julich Brain Atlas, which is freely accessible via the EBRAINS research infrastructure.

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Original publication

Bruno, A., Lothmann, K., Bludau, S., Mohlberg, H., Amunts, K., New organizational principles and 3D cytoarchitectonic maps of the dorsolateral prefrontal cortex in the human brain. Front. Neuroimaging, 3 (2024), DOI: