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New study reveals a balance of specialization and integration in the brain

In a new study in Nature Communications, scientists from Canada, Great Britain and Germany have used the Julich Brain Atlas and high-resolution magnetic resonance imaging to study patterns of organization across the whole brain and on the microstructure. The atlas is an open and interactive ressource available to neuroscientists on the digital EBRAINS research infrastructure. The results highlight an interplay between local brain areas with distinct structural and functional profiles, and global patterns which span the whole brain as cortical gradients.

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Original publication

Yezhou Wang, Nicole Eichert, Casey Paquola, Raul Rodriguez-Cruces, Jordan DeKraker, Jessica Royer,Donna Gift Cabalo, Hans Auer, Alexander Ngo, Ilana R. Leppert, Christine L. Tardif, David A. Rudko, Robert Leech, Katrin Amunts, Sofie L. Valk, Jonathan Smallwood, Alan C. Evans & Boris C. Bernhardt: Multimodal gradients unify local and global cortical organization. Nat Commun 16, 3911 (2025). https://doi.org/10.1038/s41467-025-59177-4