On September 30th, the Human Brain Project (HBP) formally completes its 10-year runtime as an EU-funded FET Flagship. The project has pioneered digital neuroscience, a new approach to studying the brain based on multidisciplinary collaborations and high-performance computing. The HBP will continue to have an impact on neuroscience for many years through the EBRAINS research infrastructure and a new way of collaborative work in the field.