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Julich Brain Atlas researchers have identified six new areas that form a functional region with a crucial role in cognitive functions of the lateral prefrontal cortex of the human brain. The team from Forschungszentrum Jülich, Heinrich Heine University Düsseldorf and RWTH Aachen University showed for the first time that the inferior frontal sulcus (IFS) and its junction (IFJ) are subdivided into six distinct areas, which are associated with working memory, language and music processing, among other functions.

Researchers of the Human Brain Project (HBP) found that in Parkinson’s disease the volumes of certain brain regions decrease over time in a specific pattern that is associated with clinical symptoms and largely coincides with the pattern described in Braak’s famous staging theory. The new study published in Cortex provides a detailed description of the structural changes over a long period of time and with an unprecedented spatial detail.